When users launch a published application in a published desktop on XenApp, the applications do not launch. However, launching the same applications outside the published desktop, works as expected.
No errors are logged in the event viewer of the XenApp server or Web Interface server when applications are launched from within the published desktop. Also, other logs reveal no errors or problems on launching the applications.
Caution! Refer to the Disclaimer at the end of this article before using Registry Editor.
Check the registry settings of the affected users to see if the following registry key is present: HKEY_Current_User\Software\Citrix\ICA Client\Engine\Lockdown Profiles
If this does not exist, copy from a working profile or download the attached template file.
The Citrix Receiver client software installation is corrupt or some required registry settings are missing.
CTX137494 - Receiver Clean-up Utility
CTX804493 - Users Prompted to Download, Run, Open Launch.ica File, Instead of Launching Connection
CTX132875 - Citrix Receiver Error 2320