Citrix Profile Management reads configurations from two registry locations. This article explains the difference between HKLM/Software/Policies/Citrix/UserProfileManager hive and HKLM/Software/Policies/Citrix/UserProfileManagerHDX hive. 

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Instructions

The registry locations are created in the following different scenarios: 
HKLM/Software/Policies/Citrix/UserProfileManager is created when Citrix Profile Management settings are configured via Citrix Workspace Environment Manager or Microsoft Group Policy (through Administrative Templates)
HKLM/Software/Policies/Citrix/UserProfileManagerHDX is created when Citrix Profile Management settings are configured via Citrix Studio or Microsoft Group Policy (through Citrix Group Policy Management)