When trying to edit a layer or publish an image with any Elastic Layering option turned on (basically, any operation where our filter drivers are involved), the machine will have a boot failure, referencing File: \Windows\system32\DRIVERS\unirsd.sys, Status: 0xc0000428, Info: Windows cannot verify the digital signature for this file.
This may also be related to a warning attempting to run setup_x64.exe to initially install the drivers on a new Gold Image, stating also about unirsd.sys, saying "Windows requires a digitally signed driver." You can ignore this warning and continue with the installation, but when you go to create layers, you will see the boot failure above.