• Published applications failed to launch on a few Delivery Groups. The issue was seen even while launching the published Notepad.
• The issue was not seen while launching published desktops.
•  After the ICA file was downloaded and launched, the application just disappeared and nothing showed up in the Connection center on the client side
• In Citrix Studio, the session shows in a connected state but no Username associated with it before the connection disconnects
•  In Citrix Director, Connection failure is logged.

Caution! Using Registry Editor incorrectly can cause serious problems that might require you to reinstall your operating system. Citrix cannot guarantee that problems resulting from the incorrect use of Registry Editor can be solved. Use Registry Editor at your own risk. Be sure to back up the registry before you edit it.

This needed further investigation from Active Directory perspective.

Active Directory team was engaged on the customer's side and it was found that they pointed Citrix VDA environment hosting the affected Delivery groups, to a domain controller in a different Geographical location. 

Pointing the subnet that had a citrix VDA's to the old Domain controller in the same Geographical location and application launches started working fine without the ApplicationLaunchWaitTimeoutMS key.

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Problem Cause

HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Citrix\wfshell\TWI\ApplicationLaunchWaitTimeoutwas set to 2 minutes (120000 ms)

More than two minutes were spent in RSOP Calculation which resulted in the application launch timing out.

VDA Event logs

Log Name:      Application
Source:        CitrixCseEngine
Date:          7/7/2023 1:40:33 PM
Event ID:      8
Task Category: None
Level:         Information
Keywords:      Classic
User:          N/A
Computer:      xxxx
Description:
The Citrix Group Policy service started RSOP calculation for user: yyy


Log Name:      Application
Source:        CitrixCseEngine
Date:          7/7/2023 1:42:40 PM
Event ID:      9
Task Category: None
Level:         Information
Keywords:      Classic
User:          N/A
Computer:      xxx
Description:
The Citrix Group Policy service completed RSOP calculation for user: yyy


Log Name:      Application
Source:        Citrix Desktop Service
Date:          7/7/2023 1:42:40 PM
Event ID:      1030
Task Category: None
Level:         Information
Keywords:      Classic
User:          N/A
Computer:      xxx
Description:
The Citrix Desktop Service detected that a user session has ended. Session 49c14096-6e4b-4386-9c32-60c46137a0c5 for user 'yyy' has ended; reason code ConnectionFailure.

VDA CDF

61956,5,2023-07-07 13:40:33:39031,13960,2012,svchost.exe(termsvcs),0,RPM,126,TriggerRSOPCalculation,11,Information,"TriggerRSOPCalculation: Calling RSOP Trigger",""

316477,6,2023-07-07 13:42:40:31653,13960,2012,svchost.exe(termsvcs),0,RPM,130,TriggerRSOPCalculation,16,Information,"TriggerRSOPCalculation: Returning from TriggerRsop",""

•    Tested by increasing ApplicationLaunchWaitTimeoutMS in registry to 5 minutes (300000 ms) and the application launched successfully.

Published Application Launch Failure Due To Delay in RSOP Calculation