"User Profile Service service failed the sign-in. User profile cannot be loaded". Error :  The volume is too fragmented to complete this transaction
 

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Option 1:
1. Create a new version in the OS layer.
2. Goto C Drive properties.

•  Tools - Run Error Checking and scan. - If any error on the scan run chkdsk /f /r from the command prompt.
•   Optimize and defragment drive - Optimize.

3. Ran the above tools and Shutdown to finish the layer.
4. Use the updated layer to publish an image.

Option 2: (PVS vDisk)

1. Make a copy of the vDisk.
2. Mount the vDisk on any server.
  
      Open Diskmanagement -> Action -> Attach VHD and select the vDisk file.
 
3. Once the disk is mount go to the Disk properties.
 

•   Tools - Run Error Checking and scan. - If any error on the scan run chkdsk /f /r from the command prompt.
•     Optimize and defragment drive - Optimize

4. Run the above and once done Detach the disk. 
 
5. Import the updated vdisk into PVS and move the production to test.
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Problem Cause

Fragmentation issue