If the requirement is to implement 2 Factor Authentication for the ADC Management GUI, it is supported from ADC Version 12.1 Build 51.16 onwards. 



Citrix ADC appliance now supports two-factor authentication for enhanced security. There is an additional layer of security added to the authentication process. 

As a result, the user identity is verified at two authentication levels. Only if passwords at both authentication levels are correct, the user is allowed to access the Citrix ADC appliance.

Previously, in single-factor authentication process, the appliance authenticated the system user only at one level of authentication.

For more information, see https://docs.citrix.com/en-us/citrix-adc/12-1/system/ns-ag-aa-intro-wrapper-con/two-factor-authentication.html