Question:
Can Citrix Gateway VPN plugin work simultaneously with Cisco AnyConnect on Windows 10?

Answer:
Our analysis shows that routing table is modify by Cisco AnyConnect client taking precedence over Citrix VPN plugin which disable access through Citrix Gateway.
The root cause for the behavior observed is related to an incompatibility between VPN clients since both use the same DNE driver on Windows system and therefore can’t coexist together with one of them taking precedence over the other.