Experiencing slowness on VIPs serving application. On testing the performance via the Netscaler and to the servers, the speed via the servers directly is much faster. 

The custom tcp profile bound to the vserver should be bound to the service group if windows scaling is enabled

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Problem Cause

The custom tcp profile bound to the vserver which has windows scaling and SACK enabled  is not bound to the service group. Hence, NetScaler is not using Windows Scaling and SACK for back end connection.

For example, client could be sending an window of 472K but in the back end NetScaler are not growing the window beyond 65k.
This is causing the slowness