When the StoreFront session times out, it's closing active ICA sessions.

We found the issue is only happening when authenticating via F5 frontend.
When Authenticating via F5. After 20 minutes the Citrix Desktop and storefront session shuts down.
After 17 minutes, a 3 mins countdown starts in the storefront browser. After 3 minutes the desktop session disappears and the browser windows displays a message “you have been logged out due to inactivity”.

Repro Steps:
- Set a session timeout duration from Storefront>Manage Receiver for Websites>Configure>Session settings
- Browse to StoreWeb URL and launch a desktop/application.
- Keep using the session and don't leave it idle.
Actual Result:
- It will disconnect the session in 20 mins.
Expected Result:
- It should keep the session active.

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A blog at F5 explains that if you used the latest iApp there is a question that controls APM's behavior to storefront session timeouts.
The question reads: "Should the iApp remove the APM session when users log out of the Web Interface or StoreFront servers?".
Try changing the answer to "No....." and see if this resolves the behavior you are seeing.
If this does not resolve it for you, there are 2 other profile idle timeout values to check. The APM policy itself has a default idle timeout value of 15 minutes which you can adjust and the TCP profile also has a idle timeout value of 15 minutes (30 if created by iApp) which you can adjust.

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Problem Cause

3rd party

Client Keep-Alive