In a published desktop or application where a smart card is required to access email, Outlook might prompt the user to “Insert Smart Card”, but a smart card is already inserted.
Remove “outlook.exe” from EnableReadImageFileExecOptionsExclusionList.
The default installation of VDA software disables hooks from Outlook.exe.
XD550VDAWX86100 introduced the registry setting EnableReadImageFileExecOptionsExclusionList.
See CTX130966 - Rollup XD550VDAWX86100 (Version 5.5.100) - For Citrix XenDesktop Virtual Desktop Agent Core Services x86 - English