Adobe Acrobat Reader Version 10 (also known as Reader X) has known issues when installed into a shared Windows 7 NxTop VM image. The application crashes when launched from the desktop or start menu, or when attempting to view a PDF document.
As a workaround, disable protected mode operation for Reader X. This is done by creating a new registry key entry in the NxTop VM image (managed by NxTop Center):
Key: HKLM\SOFTWARE\Policies\Adobe\Acrobat Reader\10.0\FeatureLockDown
OrRun the following DOS command with Administrator privileges:
reg add "HKLM\SOFTWARE\Policies\Adobe\Acrobat Reader\10.0\FeatureLockdown" /v bProtectedMode /t REG_DWORD /d 0
Note: Disabling protected mode blocks some of the new security features introduced into Adobe Reader X. You must downgrade to Adobe Reader 9. This issue is being monitored and will be updated when a new version of Reader X is available.
This issue might be related to broader issues with Reader X and user profile folder redirection that is commonly used in conjunction with roaming profiles. For background information refer to the Adobe forums.
The issue might be that the Reader X has issues navigating file system junction points when the user profile is relocated from the system disk to another location. For example, when using roaming profiles (to network storage) or in a NxTop VM (to the user disk).