Summary
This article describes how to configure Direct Server Return (DSR).
Background
The concept behind DSR is that the traffic is sourced through the NetScaler, however, the return traffic from the back-end server is sent directly to the router. Below is a sample network diagram:

Requirements
The following features must be configured on the NetScaler:
Procedure
Server-side configuration:
Create a loopback interface and configure it with the virtual IP address (VIP). The default gateway of the back-end servers should be that of the router.
More Information
Inbound traffic:
A client-side trace shows the following:
The client IP address (with the client MAC address) and VIP address (MAC address of the NetScaler).
A NetScaler trace shows the following in addition to the above:
The client IP address (because USIP is enabled) with the MAC address of the NetScaler and destination IP address of the actual server (MAC address of the real server).
Outbound return traffic:
A NetScaler trace shows the following:
The server’s IP address (server’s MAC address) destination and the client IP address (MAC address of the router).
The point behind using DSR is that you do not modify any packets. You only perform load balancing. The return traffic is sent to the router, which should know how to route it back to the client.